Supplemental Funding

Notice of Special Interest: Administrative Supplements for Activities to Promote Human Immune-Representing Oncology Models

Through funds available from the Cancer Moonshot InitiativeSM, and pursuant to the NIH interest in advancing human tissue models that do not rely on human fetal tissue (NOT-OD-19-042), the National Cancer Institute (NCI) is inviting applications for administrative supplements to improve representation of the human immune system in ongoing cancer modeling development projects that can be utilized in immuno-oncology research.

NCI supports a number of oncology model development efforts through a variety of mechanisms spanning both in vitro and in vivo model systems. Through funds available from the Cancer Moonshot Initiative, NCI is announcing the opportunity for investigators with relevant active research project grants and cooperative agreements to submit administrative supplement requests according to PA-18-591, to advance either an in vivo or in vitro model system to more closely recapitulate aspects of the human immune system in the context of the tumor microenvironment, in a manner that directly supports immuno-oncology research. Specifically, the NCI seeks to support projects that replace the use of human fetal tissue to model the tumor microenvironment with a more faithful representation of the human immune system.

In advance of preparation and submission of an administrative supplement request (i.e., application), inquiries from eligible awardee-applicants in response to this Notice (through PA-18-591), the related funding opportunity through PA-18-591, and any potential requests to appropriate NCI staff persons are encouraged.

For more details and important submission instructions lease visit the Notice at: NOT-CA-19-028

All requests, regardless of the parent award funding mechanism, must be received by 5:00 PM local time on June 3, 2019, for funding in FY 2019

Please direct all inquiries to:

Tony Dickherber, Ph.D.
National Cancer Institute (NCI)
Telephone: 301-547-9980