• HMMRATAC: a Hidden Markov ModeleR for ATAC-seq.

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• Tumor Infiltrating Lymphocytes and Macrophages Improve Survival in Microsatellite Unstable Colorectal Cancer.

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• Integrative Molecular Characterization of Resistance to Neoadjuvant Chemoradiation in Rectal Cancer.

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• Head and Neck Cancer Immunotherapy beyond the Checkpoint Blockade.

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• Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition.

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• Breaking barriers for T cells by targeting the EPHA2/TGF-β/COX-2 axis in pancreatic cancer.

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• Illuminating the Onco-GPCRome: Novel G protein-coupled receptor-driven oncocrine networks and targets for cancer immunotherapy.

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• Pas de Deux: Control of Anti-tumor Immunity by Cancer-Associated Inflammation.

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• Engineering the TGFβ Receptor to Enhance the Therapeutic Potential of Natural Killer Cells as an Immunotherapy for Neuroblastoma.

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• Immune Modulation of Head and Neck Squamous Cell Carcinoma and the Tumor Microenvironment by Conventional Therapeutics.

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• Efficient identification of neoantigen-specific T-cell responses in advanced human ovarian cancer.

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• TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8⁺ T cell exhaustion.

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• Illuminating G-Protein-Coupling Selectivity of GPCRs.

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• Protein Kinase N1 control of androgen-responsive serum response factor action provides rationale for novel prostate cancer treatment strategy.

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• Accurate Quantification of Residual Cancer Cells in Pelvic Washing Reveals Association with Cancer Recurrence Following Robot-Assisted Radical Cystectomy.

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• MUC1-C Integrates Chromatin Remodeling and PARP1 Activity in the DNA Damage Response of Triple-Negative Breast Cancer Cells.

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• Cytochrome c Deficiency Confers Apoptosome and Mitochondrial Dysfunction in African-American Men with Prostate Cancer.

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• Deep-learning augmented RNA-seq analysis of transcript splicing.

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• Early-onset triple-negative breast cancer in multiracial/ethnic populations: Distinct trends of prevalence of truncation mutations.

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• ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.

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• Impact of chemotherapy for breast cancer on leukocyte DNA methylation landscape and cognitive function: a prospective study.

  Yao S, Hu Q, Kerns S, Yan L, Onitilo AA, Misleh J, Young K, Lei L, Bautista J, Mohamed M, Mohile SG, Ambrosone CB, Liu S, Janelsins MC.
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• Differences in microRNA expression in breast cancer between women of African and European ancestry.

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• Discovery of Allele-Specific Protein-RNA Interactions in Human Transcriptomes.

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• NR4A transcription factors limit CAR T cell function in solid tumours.

  Chen J, López-Moyado IF, Seo H, Lio CJ, Hempleman LJ, Sekiya T, Yoshimura A, Scott-Browne JP, Rao A.
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• Genomic correlates of response to immune checkpoint blockade.

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• Mitochondrial hypoxic stress induces widespread RNA editing by APOBEC3G in natural killer cells.

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• Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade.

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  Immunity. 2019 Feb 19. 2(50).
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• Exosomes Produced by Mesenchymal Stem Cells Drive Differentiation of Myeloid Cells into Immunosuppressive M2-Polarized Macrophages in Breast Cancer.

  Biswas S, Mandal G, Roy Chowdhury S, Purohit S, Payne KK, Anadon C, Gupta A, Swanson P, Yu X, Conejo-Garcia JR, Bhattacharyya A.
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• Combined innate and adaptive immunotherapy overcomes resistance of immunologically cold syngeneic murine neuroblastoma to checkpoint inhibition.

  Voeller J, Erbe AK, Slowinski J, Rasmussen K, Carlson PM, Hoefges A, VandenHeuvel S, Stuckwisch A, Wang X, Gillies SD, Patel RB, Farrel A, Rokita JL, Maris J, Hank JA, Morris ZS, Rakhmilevich AL, Sondel PM.
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• Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4.

  Wang Z, Wu VH, Allevato MM, Gilardi M, He Y, Luis Callejas-Valera J, Vitale-Cross L, Martin D, Amornphimoltham P, Mcdermott J, Yung BS, Goto Y, Molinolo AA, Sharabi AB, Cohen EEW, Chen Q, Lyons JG, Alexandrov LB, Gutkind JS.
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• Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.

  Liu D, Schilling B, Liu D, Sucker A, Livingstone E, Jerby-Arnon L, Zimmer L, Gutzmer R, Satzger I, Loquai C, Grabbe S, Vokes N, Margolis CA, Conway J, He MX, Elmarakeby H, Dietlein F, Miao D, Tracy A, Gogas H, Goldinger SM, Utikal J, Blank CU, Rauschenberg R, von Bubnoff D, Krackhardt A, Weide B, Haferkamp S, Kiecker F, Izar B, Garraway L, Regev A, Flaherty K, Paschen A, Van Allen EM, Schadendorf D.
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• Upfront Therapies and Downstream Effects: Navigating Late Effects in Childhood Cancer Survivors in the Current Era.

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• MUC1-C Activates the NuRD Complex to Drive Dedifferentiation of Triple-Negative Breast Cancer Cells.

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• Immunity to commensal papillomaviruses protects against skin cancer.

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• MUC1-C represses the RASSF1A tumor suppressor in human carcinoma cells.

  Rajabi H, Hata T, Li W, Long MD, Hu Q, Liu S, Raina D, Kui L, Yasumizu Y, Hong D, Samur M, Kufe D.
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• Preclinical Characterization of ^86/90Y-NM600 in a Variety of Murine and Human Cancer Tumor Models.

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• Defining 'T cell exhaustion'.

  Blank CU, Haining WN, Held W, Hogan PG, Kallies A, Lugli E, Lynn RC, Philip M, Rao A, Restifo NP, Schietinger A, Schumacher TN, Schwartzberg PL, Sharpe AH, Speiser DE, Wherry EJ, Youngblood BA, Zehn D.
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• AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells.

  Trillo-Tinoco J, Sierra RA, Mohamed E, Cao Y, de Mingo-Pulido Á, Gilvary DL, Anadon CM, Costich TL, Wei S, Flores ER, Ruffell B, Conejo-Garcia JR, Rodriguez PC.
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• Identification of candidate neoantigens produced by fusion transcripts in human osteosarcomas.

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• Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy.

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• Preclinical Models for Studying NASH-Driven HCC: How Useful Are They?

  Febbraio MA, Reibe S, Shalapour S, Ooi GJ, Watt MJ, Karin M.
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• Leveraging TCR Affinity in Adoptive Immunotherapy against Shared Tumor/Self-Antigens.

  Miller AM, Bahmanof M, Zehn D, Cohen EEW, Schoenberger SP.
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• ⁹⁰Y-NM600 targeted radionuclide therapy induces immunologic memory in syngeneic models of T-cell Non-Hodgkin's Lymphoma.

  Hernandez R, Walker KL, Grudzinski JJ, Aluicio-Sarduy E, Patel R, Zahm CD, Pinchuk AN, Massey CF, Bitton AN, Brown RJ, Sondel PM, Morris ZS, Engle JW, Capitini CM, Weichert JP.
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• A Threshold Model for T-Cell Activation in the Era of Checkpoint Blockade Immunotherapy.

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• TCR Convergence in Individuals Treated With Immune Checkpoint Inhibition for Cancer.

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• An Alternative Skew Exponential Power Distribution Formulation.

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• A robust Pearson correlation test for a general point null using a surrogate bootstrap distribution.

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• High MYC mRNA Expression Is More Clinically Relevant than MYC DNA Amplification in Triple-Negative Breast Cancer.

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• Manifold Denoising by Nonlinear Robust Principal Component Analysis.

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• Randomized controlled trial of cryotherapy to prevent paclitaxel-induced peripheral neuropathy (RU221511I); an ACCRU trial.

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• The multikinase inhibitor RXDX-105 is effective against neuroblastoma in vitro and in vivo.

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• Development of an In Situ Cancer Vaccine via Combinational Radiation and Bacterial-Membrane-Coated Nanoparticles.

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• The empirical likelihood prior applied to bias reduction of general estimating equations.

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